Sentence examples for promoter interference from inspiring English sources

We also document the phenomenon of long-range promoter interference.

In the PhilD or PhilD* mutant derivative, transcription orientation of the kan gene was opposite that of the hilD gene, thus avoiding promoter interference.

The decrease in H3K4me3 and H3K79me2 on CCAAT promoters could in theory be due to a generalized down-regulation of these marks in Ad-YA-DN-infected cells; similarly, the disappearance of NF-YB from promoters could be the result of inhibition of NF-YB mRNA synthesis by promoter interference of the YA-DN.

To reduce promoter interference, we placed upstream of the promoters a synthetic polyA site [ 23].

However, the use of heterologous promoters can cause promoter interference, i.e., transcription from one promoter suppresses transcription from one another [ 9].

The 3.5 kb fezf2 promoter was placed in the p2 site in the opposite orientation to the p1 NβT-tauGFP cassette to minimise potential promoter interference.

Acquired loss of DNaseI in both murine and human lupus nephritis may be controlled at different levels, including activation of convergently encoded genes using sequence elements from the DNaseI gene, methylation of DNaseI encoding elements and the promoter, or interference with miRNA targeting DNaseI mRNA or other mRNAs involved in expression of DNaseI.

Therefore, the specific design of the satellite vectors is based on these three aspects: overexpression vector with different promoters, RNA interference vector, and marker-free vector.

Three mechanisms of transcriptional interference, promoter collision, promoter occlusion, and "sitting duck" interference (the dislodgement of RNAP slowly initiating transcription from one promoter by an elongating RNAP from another promoter), were proposed to explain the interfering effects of RNAP complexes acting in opposite directions [ 60].

These results show that the GR blocks the effect of oxysterols at the level of the PLA2-IIA promoter, suggesting an interference with oxysterol receptor signaling.

If it shares a bidirectional promoter then minimise interference with the adjacent locus when designing targeting strategies.