Sentence examples for promoter in the context of from inspiring English sources

The MLP may be a useful promoter in the context of a tissue-specific replicating adenovirus.

We test the promoter in the context of the efflux pump AcrB and its butanol-secreting variant, AcrBv2.

To determine whether this is a general feature of leaky-late promoters, we have carried out a detailed analysis of the VP16 promoter in the context of the viral genome at the gC locus.

The aim of this study is to investigate and select the best radiation inducible promoter in the context of viral brain tumors therapy.

To select a potent radiation inducible promoter in the context of brain tumors and to investigate if CArG radio responsive motifs or other elements in the promoter nucleotide sequences can correlate to its response to radiation.

The final step was to evaluate the modified CMV promoter in the context of an optimised Salmonella/DNA oral delivery platform.

In regard to nuclear KLF6, it could have permanent accessibility to specific gene promoters in the context of the chromatin structure of these particular cells.

We believe this system will greatly facilitate the screening of a plethora of clinically useful tumor-specific promoters in the context of oncolytic HSV vectors.

These results demonstrate that all the tested promoters, in the context of an Ad vector, possess the key characteristic of a low level of expression in the human liver, which is considered essential for use in cancer gene therapy and virotherapy.

The relative contribution of these two NF-kappaB-binding sites in the mouse iNOS promoter to hepatocyte iNOS promoter activity in the context of oxidative stress has not been characterized previously.

Recent studies evaluating promoter activity in the context of ovarian cancer gene therapy have demonstrated that even promoter activities lower than 5% can be regarded sufficient to achieve therapeutic efficacy [ 41].