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Therefore, identifying and isolating the distinct regions controlling chondrocyte specificity within specific tissues are crucial steps in using the Matn1 promoter for development of cartilage-specific transgenics.
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The minicircle vector is also a versatile tool to carry other tissue- or cancer-specific promoters for the development of promising therapeutics for other diseases.
The use, overuse and sometimes misuse of antibiotics in human and veterinary medicine are major promoters for the development and spread of multiresistant bacteria world-wide [1], [2].
Thus, Id-1 is most likely an endogenous tumor promoter for cervical cancer development.
In the last few years, it is popular to discover a gene characterized tissue-specific expression with a special promoter, for analyzing the growth and development of an important trait and applying in plant genetic engineering (Bommert et al. 2005).
Animal studies confirm that correct regulation of promoter proximal pausing is critical for development and health in adult life.
There were repeated examples of promoters creating land subdivisions with vaunted plans for development, and advertising campaigns to sell them to investors.
Selection and use of appropriate promoters, selectable markers, and reporter genes has been helpful for development of efficient protocols for transgenic rice in a number of rice cultivars.
L Hunter Lovins has been a promoter of sustainable development for over 30 years.
Our point is essentially what the reviewer has already concluded - random plus directed motility is a universal promoter of tumor development for reasons that can be traced to simple cell kinetics.
"We will work for development.
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