Sentence examples for promoter down from inspiring English sources

Consequently, the RNA polymerase is able to travel from the promoter down the three adjacent protein-coding regions, making one continuous transcript.

A possible hypothesis is that the action of WT1 on the BAX promoter down regulates BAX gene expression, thereby allowing BCL-2 to repress apoptosis.

LacI represses the tac promoter, down-regulating the otherwise constitutive mCherry transcription.

Transfection of a series of reporter gene constructs with or without S/MAR 1 (basepairs –1523 to 10077) and the more distant S/MAR 2 (basepairs –8373 to 68800), into PARP-1+/+ as well as PARP-1-/ cells, revealed an additional, major level of muPARP-1 promoter down-regulation, triggered by PARP-1 binding to S/MAR 1.

Moreover, p53 binding to the promoter down-regulated RASSF1A expression.

In the cell lines, methylation of either the upstream or downstream promoter down-regulated mRNA expression with downstream methylation being almost as effective as methylation of the entire promoter.

That means the promoter is down by almost a quarter of their gross from ticket sales before they've so much as booked a band or installed a portable loo.

As a result, according to one rule-of-law promoter, "deep down, we don't really know what we are doing .The shock of Mr Carothers's argument was salutary.

Then one year Clint Davis, the promoter, was down on the side of the stage and I said, "You gotta hear this".

The MEF2 dominant-negative mutant mMEF2 decreased TH promoter expression down to 71.3% on the T allele, but had little effect on the C allele.

These ncRNAs, discussed below in details (Fig.  1), overlap typical protein coding genes in various parts spanning from upstream regulatory and promoter regions down to the 3′ ends.