Sentence examples for promoter area from inspiring English sources

CpG islands in the promoter area of the genes were mostly unmethylated (82% of CpG islands had an average methylation lower than 10%) (Fig. 3E,F, Supplementary Data S4).

For EMSA, three different double stranded oligonucleotides, each containing a Sp1 consensus binding site, were synthesized from the predicted promoter area of the NDUFV2, and radiolabeled with [γ32P]-ATP, using polynucleotide kinase.

Furthermore, the PPRE has been recently identified in the promoter area for the catalase gene [56] and catalase has been proposed as one of the target enzymes of PPARα in rat liver [58].

However, in the current study, selected genes were analyzed using tag-SNPs ranging from the hypothetical promoter area (approximately 10 kb upstream) until approximately 5 kb downstream of the gene.

The promoter area was selected to be more resistant to methylation (the chicken β actin promoter) and in contrast to serum levels, low expression of hVEGF-A165 was present in many tissues even after 18 months as analyzed with ELISA ( Table 1) and RT-PCR (Figure 3D).

The total sequence promoter area is shown in Fig.  7B.

Aberrant DNA methylation of CpG islands has been widely observed in human colorectal tumors and is associated with gene silencing when it occurs in promoter areas.

Upon acquisition of the putative response elements in the promoter areas of vertebrate genes, a qualitative scheme is applied to assess the probability for each gene to be a hormone primary target.

Specifically, methylation of CpG-rich promoter areas (CpG islands) has been identified as an important mechanism in the dynamic regulation of gene transcription of mammalian genes [5], [6].

Search results are linked to: comprehensive annotation tools using the g:Profiler tool, which includes the presence of common regulatory motifs in promoter areas and miRNA targeting information; and, to available resources such as NCBI Entrez, Ensembl, etc.

Transcriptional regulators bind to the promoter areas of genes, thereby activating or inhibiting their transcription.