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Exact(28)
Equation 1.8 imposes an upper limit on the number of transcripts a particular promoter i can express.
OptCircuit accounts for the activating and repressing effects on every promoter i within the framework by using the modeling formulation proposed by Hasty et al. [ 25].
Specifically, the binary variable Y ij determines which transcript j is expressed from a promoter i and P j (t) quantifies the level of protein j at a given time t.
Also observe that the production of a protein j from a promoter i is turned ON if and only if the corresponding binary variable Y ij is equal to one.
S e t s : V a r i a b l e s : I = { i } = set of promoters J = { j } = set of transcripts K = { k } = set of inducers T = { t } = time P j (t ) = protein level of transcript j at time t Y i j = { 1 if transcript j is expressed from promoter i 0 otherwise The set I represents all the promoter elements investigated in this study.
"As a promoter I can only promote what you give me and if that isn't up to standard, people aren't going to buy".
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In contrast, at the HEXIM1 promoter, i-CDK9 caused a drastic decrease in the Ac-H3 level but a small increase of Ac-H4.
In contrast, at the HEXIM1 gene promoter, i-CDK9 caused a drastic decrease in the Ac-H3 level but a small increase of the Ac-H4 level.
Briefly, the CORE6 cassette includes an 18 bp I-SceI binding site (black bar), followed by a GAL1 promoter, I-SceI endonuclease gene, and KlURA3 gene (gray boxes).
M. J. Kim, a publicist, fondly described Ferriss as "the smartest self-promoter I know".
Richard Schaefer (US boxing promoter) *I would love to fight Haye in England.
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