Exact(19)
Expression in the presence of cyclosporine A promoted maturation such that mature 170 kDa P-gp became the major product (∼90% of total P-gp).
It was observed that the presence of 10 μM cyclosporine A promoted maturation of both mutants to yield the mature form of P-gp as the major product.
Immunoblot analysis of whole cell extracts showed that the V510D mutation promoted maturation of the truncation mutant but the relative level of mature was only about 20% of total CFTR protein.
Low-dose DTX did not negatively affect iDC viability and instead promoted maturation and IL-12 production.
By contrast, only VX-809 promoted maturation of mutant F337R.
Figure 4C shows that the V510R/R1070D mutations promoted maturation of ΔF508-CFTR.
Similar(41)
This same hormone has been demonstrated in the ovaries of the closely related sea urchin, where it also promotes maturation of the oocyte.
Nicotinamide promotes maturation of IPCs in the last stage.
Because mechanical loading increases during development and facilitates cardiac maturation, we hypothesized that afterload would promote maturation of EHTs.
The first injection was done to promote maturation of the eggs and the second one was to induce the release of eggs from the ovary (Shan Jian 1985).
(2018) report that high affinity and avidity immunogens are required to promote maturation of low frequency B cells in germinal centers.
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