They found that BAG3 insured the structural stability of filamentous actin (F-actin) by promoting association between Hsc70 and the actin capping protein beta 1(CapZβ1).
If KIF1C serves as a Rab6A-dependent, functionally relevant Golgi tether a protein that can connect vesicles to Golgi stacks or promote association between different Golgi stacks, like the authors suggest this kinesin must be detectable at the Golgi.
Tumor-suppressor protein neurofibromatosis type 2 (NF2 or Merlin) promotes association between E-cadherin and EGFR, links EGFR to the cortical actin cytoskeleton, and blocks its internalization, which is necessary for EGFR activation and signaling.
It has been proposed that PtdIns(4,5 P2 might promote association between the PH and DH domains, resulting in occlusion of the GTPase-binding site, whereas binding of PtdIns 3,4 P2 or PtdIns 3,4,5 P3 would cause dissociation of the domains and hence increase GEF activity.
The following has been added to the main text of the manuscript: "To examine the relevance of G-actin to the endogenous PPP1R15 complex, wild type Ppp1r15a+/+ and mutant Ppp1r15amut/mut mouse embryonic fibroblasts (MEFs) These findings are consistent with a role for G-actin in promoting association between endogenous PPP1R15A and PP1".
Hence, if SU HW) promotes associations between a LAD and a locus located in the nuclear interior, then naturally the LAD would be less frequently located at the NL.
Mayerhofer et al. (2012) thus propose that the interaction of CTR1 dimers with the ethylene receptor dimers reinforces the receptor complex by promoting associations between neighbouring ethylene receptors (Mayerhofer et al. 2012).
Thus, the often-promoted association between diabetes and pelvic floor disorders is confounded by environmental factors.
Our results support recent theoretical models which suggest, for example, that positive affect promotes associations between strong and weak concepts, and that negative affect impairs such associations [ 84].
Thus, as we have seen, amino acids can decrease Beclin1-associated PIK3C3 activity because they promote the association between Beclin 1 and Bcl-2 through inhibition of JNK1-mediated phosphorylation of Bcl-2.
