Sentence examples for promote turnover from inspiring English sources

It is presumed that in vivo, longer chain products are removed from the enzyme through membrane interactions that promote turnover.

Most commonly, addition of U residues to 3' ends is thought to promote turnover whereas the addition of A residues promotes stabilization.

Genetic interactions for crn1 ∆, as well as the late arrival of Crn1 to actin patches (Lin et al. 2010), suggest that its primary role in actin regulation may be to promote turnover (see below); thus, more work is needed to determine whether the actin crosslinking activity is relevant to Crn1's in vivo functions.

As recent studies suggest that miRNAs promote turnover of maternal and zygotic RNAs (Bushati et al. 2008; Thomsen et al. 2010), these observations raise the possibility that yar and other cytoplasmic lncRNAs may function as sponges that titrate miRNAs during embryogenesis, permitting fine-tuning of the miRNA-dependent degradation pathway.

Importantly, even though overexpression of gp78 was previously shown to promote turnover of an ERAD substrate (CD3δ) (Fang et al., 2001) whose degradation is independent of Bag6 (data not shown), the degradation of the Bag6 substrate TCRα was significantly inhibited in cells expressing gp78.

Asymmetric positioning of the various cellular components promotes turnover and movement of necessary signaling, cytoskeletal, and membranous elements.

Consequentially, these results suggest that Leo1 Paf1 promotes turnover by eviction of histones present in the chromatin.

Thus, we have included twinfilin here, with the other actin turnover machinery; however, the specific role and mechanism of twinfilin in promoting turnover remains a mystery.

These studies showed that Wpl1 indeed promotes turnover of cohesin on chromosomes and that this is counteracted by Eco1-dependent acetylation of Smc3.

Matrix metalloproteinases (MMPs) play an important part in acute and chronic inflammation, partly by promoting turnover of the extracellular matrix (ECM) and partly by modulating the action of inflammatory mediators (Parks et al., 2004).

These results suggest that Shh promotes turnover of at least a portion of ectopically expressed Ptch1 via endosomes and lysosomes, but the entry point is likely the Cav-1 positive lipid rafts rather than the conventional clathrin-coated pits.