We also minimized co-variation of codon bias with G/C islands, which might promote frame-shifting, by selectively avoiding runs of consecutive G and/or C greater than 6 nucleotides for half of the variants.
They engage in setting rules, norms and standards, they act as network hubs for public, private and civil society actors engaged around specific issues, they promote and frame health agendas and provide for health at the country level through global health initiatives and funding mechanisms.
In the latter application, the exemplars carry information about the states (the classes) that they represent, and this information should enter into the cost function, for example, in the form of the requirement that individual exemplars are promoted for frames that do correspond to a certain state (or set of acoustically similar states).
Results show a clear effect of contrast not observed in lateral masking paradigms or in 'pathfinder' stimuli, with higher contrast promoting within-frame grouping, and evidence of facilitatory interactions among parallel elements (although over a smaller scale).
The secondary structure impairs the normal movement of the ribosome during translocation, and promotes the frame-shift event in an EF-G dependent manner (Caliskan et al., 2014; Chen et al., 2014).
Based on this data, we concluded that the c.250C>T mutation may function by disruption of SF2/ASF and SC35 binding ESEs and activation of cryptic ESS sites (for binding of hnRNP I and SRp20) which promotes in-frame skipping of exon 4 from the spliced mRNA.
Our computational experiments reveal that small reward frames promote unconditional cooperation in populations with both low and high diversity, whereas large reward frames lead to cycles of conditional and unconditional strategies at high but not at low diversity.
Commercial photographs promote candy, trailer frames, chairs and tightly coiffed hairdos.
Lakoff proposes that becoming aware of how we metaphorically conceptualize or "frame" problems, including environmental crises (Lakoff 2009), is crucial to our ability to find appropriate solutions, particularly if the "frames" promote attitudes of indifference to or autonomy from nature.
This property may explain how the Ilizarov frame has been able to promote osteogenesis where other frames have failed.
PolicyMic currently receives 9 million unique visitors per month, Altchek said, and the team has learned a lot about how to frame and promote stories to give them a better chance of significant exposure to social media.
