Sentence examples for promote exacerbation from inspiring English sources

Recently, Houstis and colleagues reported that reactive oxygen species have a causal role in multiple forms of IR, a phenomenon that can further promote exacerbation of oxidative stress.

However, the underlying mechanisms for why decreased expression of IFNAR1 on DCs may promote exacerbation of colitis, whether it be through an impaired ability to induce Tregs or an inability to control proinflammatory cytokine expression, such as IL-17 and IL-13, and whether the level of receptor downregulation we observed has significant immunological effects needs to be investigated further.

The poor oral hygiene associated with the inflammation may favor the proliferation of the saprophyte oral bacteria inducing superinfection of the surgical wound and promoting exacerbation of both the inflammation and pain [ 35].

As a whole, the data presented above clearly suggest that GITR triggering promotes exacerbation of autoimmune diabetes consequent to the activation of diabetogenic T cells without significantly affecting the Treg pool.

As pulmonary DCs have also been demonstrated to play an important role in promoting asthma exacerbations in previously sensitized animals [47], we also wished to determine if the balance of allergen-presenting DCs was similarly skewed towards mDCs in genetically susceptible mice that had been previously sensitized.

The genetic data parallel clinical experience with anti-TNF therapy, which in general is highly effective in autoimmune disease but in multiple sclerosis can promote onset or exacerbations.

He said the "use of force" – meaning US military strikes – "will only lead to a further exacerbation of violence".

California certainly does not need further exacerbation of its forest fire problem.

Remaining challenges But even as local capacity is strengthened, noted Mr. Clinton, aid projects "must be based on an accurate assessment of needs" and should "promote equity and avoid exacerbation of inequality" in societies where disaster strikes.

Both are thought to promote CHF primarily through exacerbation of atherogenesis, though both may also potentiate the release of agents with direct toxicity to the myocardium itself [ 68, 69].

18 The persistence of elevated sputum PGP long after exacerbations in some individuals may contribute to continuing neutrophilic airway inflammation and promote the 'frequent exacerbator' phenotype.