The openCOBRA Project is a community effort to promote constraints-based research through the distribution of freely available software.
Staff reductions mean she is highly unlikely to be promoted; budget constraints ensure that many of the perks she came to expect have been removed.
Counteracting the pathway proactivation mechanism, binding of NSP to the kinase domain promotes steric constraints that impair intermolecular phosphorylation at Thr-474 within the NIK A-loop.
The low aspect ratio wings (typically used to maximize area under a size constraint) promote strong tip vortices, and are susceptible to rolling instabilities.
Otherwise, tensile strains at the SiNW/Si bulk interface would induce constraints that promote defects leading to a locally high silicon dissolution rate.
We combine arguments from entrepreneurship theory and the theory of recombinative innovation to construct an overarching theoretical framework that argues why resource constraints can promote, rather than impede, radical innovation.
The combination of the two architectures allows for richer dynamics that take advantage of neural and symbolic aspects of cognition and provides mutual constraints that promote convergence towards models that are both neurophysiologically and psychologically valid.
Anatomic constraints may promote or prevent the dissemination of peripheral antigenic compounds, for the vasculature in muscle is much less extensive that than in skin, which has a sprawling network of lymphatic vessels.
The participant website is tailored according to gender and includes information and messages (e.g., motivation, time constraints) to promote walking and a healthy lifestyle.
Chief among these are genes and cis-regulatory regions, which are often under selective constraints that promote their retention in related organisms.
This finding prompts a reconsideration of what we have previously termed functional pseudogenes, as RNase 8 may be responding to constraints that promote significant functional divergence from the canonical structure and enzymatic activity characteristic of the RNase A family.
