They also judge and promote based on merit.
At Pret a Manger, executives say, the answer is to hire, pay and promote based on — believe it or not — qualities like cheerfulness.
The RS domains of SR proteins bound to ESEs can also act as protein-RNA interaction modules to promote base-pairing of pre-mRNA and U5 and U6 snRNAs during the course of pre-mRNA splicing [28].
These promote base-substitutions 82, 83, frameshift mutations 84, amplification 84, mobile-intron movement 81, and transposon excision 76, 81.
In addition to the four assembly chaperones, the deubiquitinating enzyme Ubp6/Usp14 also promotes base assembly, but it is not essential.
It has been hypothesized that this stretching exposes the target bases promotes base pair exchange [29], [30].
In addition to its function of promoting base pairing of sRNAs to their target mRNAs, Hfq is also thought to engage ribosomes, poly A polymerase and RNase E and other enzymes that are involved in RNA transactions [11].
Alkylation of guanosines promotes base pairing with thymine, thereby causing G > A transitions during replication.
In the hairpin structure, a proximal stem brings the 5.8S and 25S rRNAs into close proximity, presumably promoting base pairing between them.
Under conditions of oxidative stress, p53 traslocates to mitochondria where it binds the mitochondrial DNA polymerase (Pol γ) and the mitochondrial transcription factor A (TFAM gene) and promotes base excision repair and/or replication of mtDNA.
