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Annacone also spells out the dangers: "He does a lot of innate things that are unique and this is what makes him challenging for a coach who wants to promote aggressiveness.
STAT5b and Twist have been reported to promote aggressiveness and EMT of cancer cells in HCC [16], [35].
These results indicate that OCT4 requires MYCN amplification to promote aggressiveness of neuroblastomas.
Overall, miR-210-3p miR-210-3p miR-210-3peseemsness and toerapromotestaggressivenesslls.
These results suggest that, AKR1C3-mediated steroid hormones or prostaglandin metabolism may promote aggressiveness of PCa through enhanced tumor angiogenesis.
It seems likely that other p53 mutants might cooperate via different mechanisms, independent of BMF, to convey different oncogenic signals to promote aggressiveness in human cancers.
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These data indicated that EIF5A2 induced EMT and promoted aggressiveness in BC cells.
Deficiency of p53 modifies tumor biology, promoting aggressiveness, rapid growth and genetic instability.
Here, we found that OCT4 promotes aggressiveness of MYCN-amplified neuroblastoma cells by forming a positive regulatory loop with MYCN/NCYM (Fig. 6).
Our study suggests a model of tumor progression in which elevated miR-182 expression and subsequent down-regulation of MTSS1 promotes aggressiveness of HCC.
Based on our results, miR-210-3p promotesurvivalal of GBM cells in the tumor microenvironment, promotes aggressiveness by imparting temozolomide resistance and targets HIF3A, which is known to function as a negative regulator of hypoxia-inducible gene expression [ 24].
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