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Mr. Baitz was still in his "promising" phase, which — to be honest — he seemed to inhabit for the succeeding decade and a half.
This is a company with a very clear near-term catalyst, omadacycline, an oral antibiotic for bacterial skin infections, that in July released promising Phase III data meeting all endpoints required by the FDA and EMA for review.
Nivolumab (BMS-936558), a fully human IgG4 PD-1 immune checkpoint inhibitor, is currently being evaluated in two Phase III trials for NSCLC after promising Phase I data.
However, many drugs did not make it through Phase 3 clinical trials despite promising Phase 2 trials, such as bardoxolone [ 33].
Following the promising Phase I data, the current Phase II study (ClinicalTrials.gov, NCT01024920; Study 1199.26) evaluated the safety and efficacy of nintedanib as first-line therapy for previously untreated patients with advanced RCC.
The collateral damage resulting from these failures is staggering; novel treatments, many with compelling mechanisms of action and promising Phase 2 trial results, never reach the patient, adversely affecting small and large pharma alike.
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Celgene shares jumped 18% last Monday after the biotech firm announced promising Phase III results for its experimental bone cancer treatment Revlimid, considered by many to be the biotechnology firm's key earnings growth driver.
Nick Clegg's party had gone into the general election promising to phase out fees.
Countries throughout the world have signed a treaty promising to phase out its use.
The junior coalition partner had gone into the general election promising to phase out fees.
Glossier responded by promising to phase out the foil packaging and reformulate its glitters to be biodegradable.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com