Sentence examples for promiscuous activity from inspiring English sources
Abstract Inappropriate kinase expression and subsequent promiscuous activity defines the transformation of many solid tumors including renal cell carcinoma (RCC).
Promiscuous activity and gain-of-function mutations in EZH2 are documented in a wide range of human cancers prompting interest in its potential as a therapeutic target32.
Heavy drinking and promiscuous activity does obviously play a large part of university life, but it's not the norm for every undergraduate.
The present study uncovered several enzymes with promiscuous activity and it revealed that host metabolic pathways compete with the heterologous pathway for 4-HO-Thr.
To overcome these limitations, we developed an "IPP-bypass" isopentenol pathway using the promiscuous activity of a mevalonate diphosphate decarboxylase (PMD) and demonstrated improved performance under aeration-limited conditions.
Advances in protease engineering for laundry detergents comprise simultaneous improvement of thermal resistance and activity at low temperatures, a rational strategy to modulate pH profiles, and a general hypothesis for how to increase promiscuous activity towards the production of peroxycarboxylic acids as mild bleaching agents.
Previous studies have utilized activated mutant variants of non-receptor tyrosine kinases like SRC to identify downstream substrates of this kinase subfamily; however, these overexpressed, constitutively active mutants likely display promiscuous activities that do not necessarily reflect the substrates of the endogenous protein when activated by an upstream RTK.
In contrast, chimeric enzymes previously constructed by homology-independent recombination of hGSTT-1 and rGSTT2-2 exhibited very different substrate promiscuity profiles, and showed a more defined relationship between evolved and promiscuous activities.
Many enzymes possess, besides their native function, additional promiscuous activities.
Examples for variants exhibiting large improvements in promiscuous activities and small changes in native activity.
In addition to catalyzing acyl transfer reactions, a number of promiscuous activities have been described recently.
