Sentence examples for prominent pathway models from inspiring English sources

To create the corpus, we initially selected from the PANTHER DB a set of prominent pathway models of interest that were familiar to our domain experts: the p38 MAPK, p53, p53 feedback-loops and Wnt signalling pathways.

The same model applied to ibuprofen shows that usage is a more prominent pathway than it is for metoprolol.

The most prominent pathway involved in RAS-mediated apoptosis is the Raf ERK pathway.

Another prominent pathway for protein degradation is the ubiquitin-proteasome system.

FGF signalling is a prominent pathway that controls epithelial cell proliferation during embryonic development.

The PI3K/Akt signaling axis is a prominent pathway with a dual action with respect to influenza viruses [ 34].

Hemichannels could serve as prominent pathways for Ca2+ entry facilitating the above-mentioned processes.

The best characterized and the most prominent pathways leading to apoptosis are called the extrinsic and intrinsic pathways.

Also, 33 pathways were identified (P < 0.05, Additional file 10), and the most prominent pathways among them were regulation of actin cytoskeleton, MAPK signalling pathway, and tight junction.

Here, after a brief review of modelling human cancers in the mouse, we will discuss many of the prominent MB mouse models (categorized according to signaling pathway) published since 1997, when the first Ptc+/− mouse model was generated.

One prominent example of global models are active appearance models (AAMs) [23 25].