Sentence examples for prominent pathological changes from inspiring English sources

Although the pathogenesis of AAA formation and progression remains poorly understood, chronic inflammation, enzymatic degradation of elastin and collagen, and malignant vascular remodeling constitute the prominent pathological changes associated with AAA.

Our results showed prominent pathological changes in the liver tissue of MTX-treated animals including inflammatory cells infiltration, severe centrilobular/intermediate zone/ periportal degeneration, bile duct hyperplasia, hyperemia and necrosis observed compared to control and turmeric groups.

The most prominent pathological change was the development of atrophic muscle fibers with mild necrosis and inflammatory infiltration.

The most prominent pathological change was the angular-shaped atrophic muscle fibers in the muscle, which were not seen in the control mice.

These deficits occurred well before plaque deposition became prominent and may, therefore, reflect early pathological changes, likely induced by intraneuronal APP/Aβ mistrafficking or intraneuronal Aβ accumulation (reviewed in [ 1]).

While their spatiotemporal development parallels the appearance of non-motor and motor symptoms [ 10], little is known about changes in microglial activation, another prominent pathological feature of PD [ 11– 13].

Physiological and pathological changes in cardiac workload can cause prominent alterations in gene expression [1].

In early disease phases, the pathological changes consisting of focal and/or perivascular inflammatory infiltrates (with a prominent number of CD8 positive T cells), microglia activation, astrocytosis and single neuronophagia are limited to the superficial and deep cortical layers.

The observation of disseminated histoplasmosis with prominent gastrointestinal involvement, no respiratory symptoms (which is presumed to be the portal of infection), gastrointestinal pathological changes, and minor digestive system disorders make this case study exceedingly rare.

Atypical scrapie (AS) cases have been characterized by the distribution of pathological changes and deposits of the disease-associated isoform of the prion protein (PrPSc), which have been most prominent in the cerebellum.

Pathological changes were found in all patients.