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The lockout began in June, and while a fight over the officials' pensions was the most prominent hurdle — and the final one that the sides worked on late Wednesday — the league also sought more control over grooming and replacing officials, in the name of improving officiating long term.
For the majority of non-viral siRNA carriers studied so far, endosomal confinement is identified as the most prominent hurdle, limiting the full gene silencing potential.
Thus, even though CDDP provokes moderate-to-severe adverse effects in a fraction of patients, the most prominent hurdle related to the use of CDDP in the clinical practice is posed by the elevated incidence of chemoresistance, be it innate or acquired.
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Another big hurdle".
Two big hurdles remain.
big hurdles?].
Regulatory hurdles remain prominent for translation of the most novel agents, but microdosing protocols are being adopted for some and programs such as DCIDE will continue to shepherd the most promising new contrast agents and probes to the clinic.
China's image abroad, particularly in the United States, faces two major hurdles, said Hung Huang, a prominent media commentator in Beijing.
Despite potential concerns about regulatory and political hurdles, the deal already has one prominent backer.
A group of lawmakers and prominent technology investors are trying to ease bureaucratic hurdles for thousands of foreign-born entrepreneurs as part of a broader effort to create jobs in the United States and spur innovation.
One wonders if our unwillingness to bring more prominent defendants to court is, in its own way, creating another hurdle for the prosecution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com