The phrase 'prominent hub' is correct and usable in written English.
You can use it to describe an important location in a city, such as a town square, business district, or transportation hub. For example, "The city's main train station is a prominent hub for commuters."
Interestingly, CDKN1A, the gene encoding p21Waf1/Cip1, is a prominent hub linking many of the genes within the 'cell cycle' signature, consistent with studies identifying p21Waf1/Cip1 as an important effector of c-Myc action on the cell cycle in estrogen-treated cells [13], [19].
Among the most prominent hub genes was App: its promoter is un-methylated in the treated mice.
Among the most prominent hub genes was App, which is a protein that helps direct the migration of neurons during early development (Priller et al., 2006).
One prominent hub in the IPA-derived associated network functions was the insulin protein complex, including the insulin hormone and insulin-like growth factor proteins.
Constitutive activation of NF-κB impedes activity of the tumor suppressor p53, a prominent hub in DNA-induced cellular stress networks and regulator of cellular senescence [ 67].
In ER+ breast cancers, for both cohorts the ESR1 gene encoding ER alpha (ER α) was the most prominent hub of a large interconnected network, consistent with its central role in this cancer subtype.
A scale-free network displays high degree of tolerance against random failures as only a few prominent hubs dominate their topology.
They uncovered that employees who were prominent hubs of giving and receiving kudos from both inside and outside of their workgroup outperformed their colleagues.
In the 1700s, and on through the 1800s, Charleston was one of the most prominent hubs for the slave trade in North America.
In addition to analyzing the prominent hubs in the interaction network, we also examined the relationship between connectivity of TFs, sequence conservation, and known function.
Other prominent hubs include pal-1 (conserved among nematode species), as well as other TF genes with orthologs in nematodes, fly, mouse, and human: tag-331, eya-1, and sma-4.
