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Aberrant DNA methylation patterns are a prominent hallmark of cancer cells (Hanahan and Weinberg 2011).
Thus, the evasion of apoptosis is a prominent hallmark of cancer [ 8].
Diffuse and focal WM lesions are another prominent hallmark of SVD 54.
Immune phagocytosis pathway and CYBA gene: One prominent hallmark feature of cancer is the evasion of immune destruction [ 39].
Accumulation of ECM components in the mesangial area is a prominent hallmark of DN, which ultimately results in renal fibrosis [ 50, 51].
The accumulation of aggregated proteins, extracellular amyloid β (Aβ) in the senile plaques and intracellular Tau protein in neurofibrillary tangles, is a prominent hallmark of AD (74).
Similar(51)
Morphological control during mineral crystallization is one of the prominent hallmarks of biomineralization.
Vazquez-Fresno et al., used NMR-based metabolomics to assess the effect of an Mediterranean diet on urinary metabolome and revealed that the most prominent hallmarks concerning Mediterranean diet groups were related to the metabolism of carbohydrates, creatine, creatinine, amino acids, lipids and microbial cometabolites.
The most prominent hallmarks of these changes are a decrease in taurine levels and changes in choline metabolism, characterized by increased levels of TMA, TMAO and DMA.
The prominent hallmarks of gliomas are their characteristics of malignant proliferation and aggressive invasion.
H3K4me1 and H3K4me3 also were prominent hallmarks although with weaker signal intensity than that observed in the vegetative macronuclei (M in Figure 2C, D), and H3S28p occurred as scattered foci-like signals in the fragmented parental macronuclei (p).
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