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Although glucose can generate ATP via glycolysis, its most prominent function is evidently in anabolism (biosynthesis).
To further test for dfoxo-to-other signaling, we manipulated the levels of dfoxo in cells whose prominent function is in adult endocrine signaling.
In contrast, while Tip60-p400 promotes expression of some genes required for cellular proliferation and cell cycle regulation in ESCs, its most prominent function is to silence genes that are active during differentiation (Fazzio et al., 2008a, 2008b).
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One of the most prominent instantiations of the function is as follows.
The most prominent inhibitor of LOX function is the small-molecule inhibitor β-aminopropionitrile (BAPN) [ 15, 21].
As single ethylene mutants do not display a visibly prominent phenotype, ethylene receptor function is inferred from phenotypes of mutants defective in multiple receptors [ 12].
Another prominent choice of the distance function is PAM74-100 [ 47].
Reduction of MUC2 expression is frequently seen in ulcerative colitis patients and other inflammatory bowel diseases where loss of barrier function is a prominent clinical feature.
In more detail, in case of exclusively LA Maze ablation, it has been proved that, despite successful SR restoration, the progressive loss of LA function as well as LV diastolic function is more prominent in patients affected by rheumatic disease with respect to those with degenerative prolapse [ 26].
PPAR-γ expression is prominent in adipocytes and its function is best described in regulating lipid metabolism, but PPAR-γ plays a more general role in cellular proliferation, differentiation, and survival, as well as acting as a negative regulator of inflammation [ 2, 3].
Although previous data suggest that telomerase-based models of accelerated aging have osteoporosis, our current study shows that these models reflect the major features of senile bone loss, and that impairment of osteoblast function is a prominent aspect of accelerated bone aging.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com