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In order to identify cellular processes on which prednisolone has a prominent effect, a gene set enrichment analysis was conducted using the 518 probe sets that were differentially regulated in WT mice by prednisolone.
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Interestingly, the mechanism by which p38 exerted such a prominent effect involved a novel feedback loop that controlled signal amplification at a level that was immediately proximal to the BCR.
Researchers said this could be because finishing college can have a more prominent effect on a person's ability to land a good-paying job, regardless of whether or not they had borrowed to pay for those degrees.
Given the prominent effects of A-to-I editing on transcriptome, it is not surprising that aberrant A-to-I editing contributes to various diseases.
For non-Ph mTBI, the most prominent effect is a bilateral swelling of the brainstem at the pons/medulla junction and at the level of the pons-midbrain junction (shown in the posterior view of the brainstem; Fig. 3A).
The most prominent effect was a marked dephosphorylation of the AKT protein, which is one of the major kinases that phosphorylate telomerase in the cell.
We found that a prominent effect of nocodazole was a block in separation of centriole pairs, and a tendency of centriole pairs to aggregate at their distal tips, assuming a tip-to-tip configuration.
A-770041 had a prominent effect on the accumulation of Calcein in KHOSR2 cells at a concentration as low as 0.01 μM.
Mono-treatment with either inhibitor resulted in reduction of tumour sizes as compared to the control group, and a tendency to a more prominent effect in the group given a combination of the two drugs was observed (Fig. 3).
The model is shown to have a prominent effect on NO predictions, with an improvement in the regions close to the nozzle.
Baclofen is a GABA-A receptor agonist which can have a prominent effect on the motor tone via direct hyperpolarization of the motor horn cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com