Sentence examples for prominent differentiation from inspiring English sources

We suspected that the prominent differentiation toward gonadotroph fate at these stages could be due to the estrogen (E2) receptor modulator tamoxifen.

Additionally, the expression patterns of prominent differentiation marker genes in cartilage (aggrecan, Col2a1, Col10a1 and Mmp13) were compared by qRT-PCR (Fig.  2b).

In the presence of EGF, HepaRG cells show a prominent differentiation pattern toward hepatocyte-like cells, though smaller amount of biliary epithelial-like cells also persist (Parent et al. 2004).

E2 effects on endocrine cell proliferation and numbers in males are relatively nonspecific within the different endocrine populations, with maybe a slightly higher sensitivity of lactotrophs (Castrique et al., 2010; A. Levy, personal communication) but we observed, in responding animals, prominent differentiation of the stem cells in the main anterior lobe endocrine population, GH+ve somatotrophs.

LY294002, which is a specific PI3K inhibitor, was shown to cause prominent cell differentiation in human ES cells [7].

Furthermore, we corroborated prominent muscle differentiation and neuromuscular disease-associated miRNAs.

Thus, out of the GFP+ HNPCs the most prominent neuronal differentiation was found in Groups 2 (79%) and 3 (72%).

Widespread apoptotic cell death ensued after 5 7 days leaving approximately 10 20% of cells intact, characterised by prominent neuroendocrine differentiation.

The AP of control and Bmpr1a-CKO mutant mice developed normally with respect to gross morphology and hematoxylin and eosin sections at stage P14, when prominent epithelial differentiation was observed.

However, with all the limitations due to the small sample size and to the lack of a specific assay in vitro assay, we can speculate, according to the data from Ko et al. [ 17], that the presence of the TET2 mutation can induce a second clone with a prominent monocytic differentiation.

Histological analysis of H&E stained tumor sections revealed poorly differentiated spindle-shaped tumor cells with prominent squamous cell differentiation and extracellular keratin deposition (not shown).