Sentence examples for prolonging life span from inspiring English sources

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While this is a huge challenge for medical science, there is hope that new therapies will be developed that enable several so-far-incurable diseases to be cured, prolonging life span and improving the quality of life.

AMPK's important role in aging is further underscored by the evidence (Anisimov et al. in this issue of Aging) that metformin treatment is more effective in prolonging life span in female mice when started early in life [ 76].

To date, klotho gene delivery is shown to effectively rescue many phenotypes observed in klotho-deficient mice, prolonging life span, 117 attenuating the progression of hypertension and kidney damage in spontaneous hypertensive rats, 118, 119 ameliorating angiotensin II-induced kidney injury, 120 improving endothelial function, 121 and protecting from uremic cardiomyopathy.

Exercise also typically is recommended as a means of fighting heart disease and prolonging life span.

Our results shed light on early reports that showed favourable effects of chronic long-term Ang II inhibition by either ACEi or ARBs in protecting rats from the deleterious effects of aging on cardiovascular system and prolonging life span (Basso et al, 2007).

Similar(55)

"Our underlying hypothesis is that this drug would prolong life span," Dr. Longo said.

They emerged as the surprising outcome of a quest begun in 1991 by Leonard P. Guarente of M.I.T. to look for genes that might prolong life span in yeast, a single-cell organism.

The theory that resveratrol activates sirtuins, which then prolong life span, is popular because of the notion that drinking red wine can make people live longer, but it "should have been abandoned five years ago," said Richard A. Miller, who studies aging in mice at the University of Michigan.

We show that IM in combination with proteasome inhibitor significantly prolongs life span of BALB/c mice bearing BCR-ABL/GFP-expressing murine hematopoietic cells (Figure 1, Figure S1 and S2), and suppresses tumor growth in nude mice harboring K562 cells (Figure 2).

A few combinatory regimens were evaluated and the results showed that IM (20 mg/kg) in combination with BOR (0.2 mg/kg) significantly prolonged life span of mice as compared to vehicle (P<.0001), BOR alone (P = .0026), or IM at 20 mg/kg (P = .01).01

With prolonged life span, there is an increasing number of elderly people with aging-related degenerative diseases.

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