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At present, the selection of a specific drug for an individual patient is largely undertaken on a trial-and-error basis (7, 8), frequently leading to prolonged trials of medication, development of significant side effects, and greater health care costs (8, 9).
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However, obtaining meaningful change in these indices may prolong trial duration, increase sample size and cost, and be influenced by variation in respiratory intervention and end-of-life care at different institutions.
A drop of water was given after each correct trial; errors were indicated by a low white-noise sound and sanctioned by a slightly prolonged inter-trial delay.
They included prolonged pre-trial detention for 80% of all prisoners in Haitian jails; institutional "brittleness" on account of long-delayed elections to the Senate and local bodies; rising homicide rates; and a depressing predilection for public lynching, which indicates little confidence in the justice system.
Conversely, delivery of the intervention may degrade with time if the recruitment period is prolonged and trial fatigue develops.
25 Although corticosteroid treatment has been associated with low toxicity in several trials, prolonged treatment seems to lead to weakness, delirium, osteoporosis and immunosuppression, all of which are commonly present in advanced cancer patients.
Furthermore, assessment of the clinical, pathological and molecular biological responses [ 13, 14] can confirm the superiority or inferiority of new agents much faster and more reliably than prolonged randomized controlled trials presently conducted in stage IV [ 15].
Article accuses the tribunal of irrelevancies and reduncancies which prolong the trial; and that our legal men are completely lacking in knowledge of Europe, polictically and historically.
Rather than anger the judge and prolong the trial, the states abruptly withdrew the witness, James Bach, last week after Microsoft told the judge it would take several weeks to prepare to cross-examine him.
This June, researchers announced that an antiangiogenesis drug, given with conventional chemotherapy drugs in a large clinical trial, prolonged the lives of patients with advanced colon cancer.
Forensic psychiatrist Dr Philip Joseph told her trial prolonged amphetamine abuse had badly affected Ms Jenkins's mental state so she was convinced the mafia was out to get her.
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