A previous study of patients with bilobar HCCs diagnosed after laparoscopy or laparotomy has shown that combined resection of HCC in one lobe and wedge resection or ethanol ablation of lesions in the contralateral lobe greatly prolonged the long-term survival compared with nonsurgical treatments.
The ability of EGCG to prolong the long-term effects of cysteamine adiministration beyond its discontinuation, was confirmed in vivo in Cftr F508del mice.
On the other hand, prolonging therapy in the long term in patients at relatively lower bleeding risk (that is, those who tolerate this therapy for at least 12 months) could result in a more favourable reduction of ischaemic events, at the cost of some major haemorrhagic complications.
Clinical randomised studies such as the Diabetes Control and Complications Trial and the Epidemiology of Diabetes Interventions and Complication have shown that early intensive glycemic control reduces risk, whereas prolonged hyperglycaemia can increase the long term risk of diabetic complications (Kilpatrick et al., 2009).
Remanufacturing is a process which allows decreasing and rationalising the quantities of materials used by recuperating parts of products at the end of the use phase, subjecting them to renewal treatments and then inserting them into new products, therefore prolonging their exploitation (over the long term).
Because the development of diabetes requires deterioration of glucose metabolism over the long term, prolonged and persistent exposure to POPs may be an important factor in a putative causal pathway linking POPs and diabetes.
But with Beijing's priority of protecting jobs, China's state-owned, industrial sector is prolonging its earnings slump in the long term by maintaining production — now overproduction — which contributes to depressed prices.
"A lot of people take vitamins because they believe it will benefit their health in the long term and prolong life," said Edgar R. Miller III, an associate professor of medicine at the Johns Hopkins University School of Medicine, who led the research.
In that sense, prolonged MV appears to reduce life quality and expectancy in the long term [ 34, 37, 38].
Prolonging a minor inconvenience in the short term can save you problems in the long term.
Over the long term, however, he said that higher rates could compound Europe's larger problem of prolonged economic weakness and slow its recovery from the current recession.
