Sentence examples for prolonged target from inspiring English sources

Therefore, selective proteasome inhibitors with optimized pharmacokinetics may achieve similar or even prolonged target inhibition with reduced toxicity.

Interestingly, we never observed a complete loss of these molecules even after prolonged target cell contact (data not shown).

However, fixed dosing resulted in increased systemic mAb exposure and prolonged target occupancy in pediatrics, with decreasing age, decreasing dose and increasing target concentration.

Compared with bortezomib, more selective epoxyketone-based proteasome inhibitors should be capable of prolonged target inhibition by avoiding boronic-acid-based off-target toxicity.

Antibodies by nature are stable proteins, and m909 should have a relatively long half life in circulation, providing an option when prolonged treatment targeting FRβ is desired.

The uniform distribution of the beam on target is required in some high power beam applications to prolong the target lifetime or to improve the beam utilization.

Generally, the target for sputtering TCO films should have a high density, finer grain size, and better conductance[7 11], which will be helpful for avoiding the formation of nodules to prolong the target lifetime[7, 8], increasing the deposition rate and film uniformity[9] and meeting the requirement of direct current (DC) sputtering.

If anything, they exacerbate and prolong the targeted outbreak.

The government offered a road map for the peace talks; American bombing of IS targets prolonged Kobane's resistance and thus reduced the pressure on Turkey to intervene.In this section Sedating, not leading Order, order!

As a matter of facts, the cell-based delivery system possesses a number of advantages including prolonged delivery times, targeting of drugs to specialized cell compartments and biocompatibility.

Although in vitro potency of VRS-317 was reduced approximately 12-fold compared with rhGH, in vivo potency was increased because of the greatly prolonged exposure to the target tissues and organs.