Sentence examples for prolonged signal from inspiring English sources

In the context of NF1 such mechanisms are likely to be extra-ordinary effective because prolonged signal transduction takes place in NF1 deficient cells [16].

The assumption of stationarity may also be violated with prolonged signal recording.

Abrogation of p53 function by mutation could thus prevent cells from sensing an abnormally prolonged signal, leading to loss of growth arrest, reduced apoptosis and differentiation, and consequent outgrowth of less differentiated cells.

The more efficient activation of naïve T cells by CD81 was due to prolonged signal transduction compared with that by CD28.

The simulation result also shows that inhibition of non-clathrin dependent endocytosis increases TGF-β signal amplitude, which produces a prolonged signal (Figure 6C).

The continuous and intermittent models were used in case the loss of PTEN resulted in a prolonged signal for muscle growth that was obscured in the continuous overload paradigm.

A recent and surprising finding for the PTHR1 is that it can form highly stable complexes with certain PTH ligand analogs and thereby mediate markedly prolonged signaling responses in cells and in animals.

In addition, the activation and the prolonged signaling via AKT1 inhibits forkhead box subfamily O (FOXO) transcription factors by mediating their phosphorylation and sequestration in the cytoplasm, resulting in transcriptional changes that increase glycolytic capacity [32].

The double-cue induced synergistic and prolonged signals in early visual areas, the motion specific visual area V5, PPC, and the supplementary and frontal eye field.

Although both ligands evoked qualitatively similar signaling activities and early transcription, HRG induced prolonged signaling activities and significant expression of c-FOS protein, while EGF induced a transient signal and negligible amounts of c-FOS.

The temporal profile of the Ca2+ signal determines the magnitude of response obtained, so that although short bursts of Ca2+ elevation are sufficient to initiate gene transcription, prolonged signalling is required for a maximum response [20].