The phrase "prolonged persistence" is grammatically correct and can be used in written English.
It means the act or state of persisting for an extended period of time. It could be used in a variety of contexts, such as discussing someone's behavior or a problem that has lasted for a long time. Example: Despite numerous setbacks, her prolonged persistence eventually paid off and she finally achieved her dream of becoming a doctor.
At least in some cases, prolonged persistence of adoptively transferred T cells may be valuable for prevention of late cancer relapse in adoptive hosts.
The rapid blood clearance of these nanomaterials could prove beneficial when using short half-lived radionuclides in diagnostic applications, as prolonged persistence of blood-pool activity following antibody-construct administration obscures target imaging due to a low signal-to-background ratio.
Such risk could result from impaired defense against liver and/or blood-stage parasites and from prolonged persistence.
Thus horizontal transmission only occurs upon host death, and the horizontal transmission stage has prolonged persistence outside of the host.
This process enables prolonged persistence through a masking or steric hindrance effect, which prevents interaction with the host immune cells (27, 34 ).
Similar effects on histone γH2AX, for example, prolonged persistence of DNA damage measured by this sensitive marker, have been shown in several studies using HDAC inhibitors that indirectly block Hsp90 by acetylation (Zhang et al, 2007; Zuco et al, 2010).
However, the growing knowledge of antibody interactions with FcRN receptors resulting in prolonged serum persistence have allowed for development of engineered antibody fragments possessing shorter half-lives while providing the same specific binding to their antigen.
This critical balance between these two cytokines was sufficient enough to induce Th1 response, as well as, the presence of small amount of IL-10 limits the self killing mechanism of Th1 cells and thereby prolonged its persistence.
In these cases, blood half-life may paradoxically be relatively short despite the prolonged body persistence [ 65].
Taken together, these results demonstrate that S. aureus dynamically alters its agr and virulence factor expression to bypass innate immune defences and establish conditions favouring prolonged intracellular persistence.
Compared to the wild type, this strain showed improved bile resistance in vitro and prolonged gastrointestinal persistence and protection against L. monocytogenes infections in mice.
