In both cell lineages, prolonged assays (6 hours) showed that a mature biofilm that masked the LA phenotype had developed.
When stimulated with G-CSF in vitro, SOCS3-deficient cells of the neutrophilic granulocyte lineage exhibited prolonged STAT3 activation and enhanced cellular responses to G-CSF [ 46, 47].
These observations indicate that certain FYVE and PX domain-dependent functions are likely to have emerged early in the evolutionary process as selective domain combinations are present in all taxonomic groups and also the high association frequencies of these combinations suggest that they have been retained even through prolonged evolutionary changes of eukaryotic lineages.
In the case of Brazil, the LAM lineage supremacy likely mirrors the persisting influence of the prolonged, major immigration from Southern Europe and Africa, where this lineage is widespread as well [13], [48].
However, dysfunctional recognition of self-antigens as nonself-antigens results in autoantibody production, sustained by plasma cells derived from the B-cell lineage that survive for prolonged periods in the lymphoid tissues.
Integration of fossil, archeological, sedimentary, and paleolandscape evidence illustrates the potential influence of prolonged high variability on the origin and spread of critical adaptations and lineages in the evolution of Homo.
If the pattern of molecular dating inferred from mtDNA and Y chromosome data is a true reflection of gibbon matrilineal and patrilineal histories, the delayed divergences occurred among paternal lineages might raise speculation of prolonged male-biased gene flow.
Ye, R. et al. Impact of tamoxifen on adipocyte lineage tracing: inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase.
The extended duration of concerted evolution in multiple distant lineages suggests that there has been prolonged homogenization of specific segments within these gene pairs.
The ability of adipose-derived stem cells (ASCs) to undergo prolonged periods of expansion and differentiation towards specific lineages has made them a valuable cell source for clinicians and researchers interested in tissue repair and regenerative medicine.
These hiPSCs have the characteristics of hESCs, including prolonged growth in culture and differentiation to multiple tissue lineages.
