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Numerous problems exist for current treatment strategies for chondral and osteochondral defects including but not limited to donor site morbidity, multiple surgeries required, prolonged limitations in activity, and significant financial costs [ 7- 10].
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Analysis of a Atpht1 9 1 mutant and pht1 8/pht1 9 silencing lines suggested a role for AtPHT1 9 and AtPHT1 8 in Pi acquisition at the root-soil interface during prolonged Pi limitation [ 28].
While there is no evidence so far of a direct role for urea metabolism in the EPN lifestyle, a potential role for these pathways can be exemplified by current research on diatoms where the urea pathway is a key to facilitating rapid recovery from prolonged nitrogen limitation followed by rapid growth under nutrient rich conditions [ 6].
The National Institute for Health and Care Excellence NICEE) recommends surgery when there is prolonged and established limitation and severe pain.
However, delivering the active enzyme for prolonged periods presents practical limitations.
According to the historian David Marr, there was evidence that Phan clearly realised the advantages and limitations of prolonged resistance.
The act prolonged the statute of limitations to file employment discrimination claims -- in other words, the Act extends the amount of time that women are able to file an employment discrimination claim.
Likewise, monitoring of physical limitations during prolonged sick leave may help to identify those at risk for work disability.
(Participant #1) Nine participants discussed how CLD symptoms adversely affected their daily activities, while nine participants reported professional limitations, including prolonged absences from work or school or the need to enroll in a disability program.
Childhood chronic disease was defined according to a three-axis framework [ 13], where the condition is assumed to have a biological, psychological or cognitive basis, being prolonged in time, and causing limitations in function or dependency on continuous therapy or services.
"It's always about damage limitation and then prolonged frustration, we've managed it in periods - the first 45 minutes against Poland [a 7-0 home loss], even with the Germans [4-0 iNuremburgrg].
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CEO of Professional Science Editing for Scientists @ prosciediting.com