Sentence examples for prolonged levels of from inspiring English sources

In contrast, recombinant adeno-associated viral (rAAV) vectors that allow to achieve higher and prolonged levels of transgene expression may be more adapted for translational approaches (Frisch et al. 2015b).

Prolonged, significant sox9 overexpression via rAAV was achieved in the aspirates for at least 28 days when applying the rAAV-FLAG-hsox9 construct, leading to higher, prolonged levels of matrix biosynthesis and to enhanced chondrogenic activities relative to control treatments especially when maintaining the samples under mechanical stimulation.

In contrast, both WT and iSTAT3β MEFs showed prolonged levels of nuclear retention of phospho-STAT3 at 60 min post-treatment with OSM.

Proinflammatory cytokines (endogenous pyrogens) have a central role in the genesis of fever, and high and prolonged levels of cytokines are expressed in patients with severe sepsis [ 12, 13].

Therefore, prolonged levels of contact between persons in semi-closed institutions such as hospitals, residential-care facilities, and schools facilitate person-to-person spread to an extent not seen in other settings, which in turn leads to more prolonged outbreaks.

For others, however, heavy workload compounded by feelings of limited control, self-criticism, balancing home and work demands, or difficulties at work have been associated with high levels of psychological distress [ 5- 7] and it is recognised that prolonged levels of excessive stress may lead to low morale [ 8].

Some may cause cancer only after prolonged, high levels of exposure.

Research suggests prolonged high levels of cortisol are a direct risk factor for chronic disease and increased mortality.

It was noted that H2O2 strongly increased and prolonged phosphorylation levels of eIF2α or JNK (Figure 2C).

It is therefore likely that prolonged elevated levels of IFN-γ in mice vaccinated with Mdh contribute to the reduction in the colonization by S19 in these immune animals.

We envision that the IMDDS will be capable of providing a relatively safe method of administrating prolonged therapeutic levels of drugs.