Sentence examples for prolonged association from inspiring English sources

The presence of the higher-mass forms suggests the possibility of improper folding of the Mec1 derivatives, or perhaps prolonged association with chaperone complexes that are required for the formation of functional PIKK proteins (Boulon et al. 2012; Makhnevych and Houry 2012).

It was shown that the insulin secretion defect was because of an increased rate of glucose-stimulated translation that overwhelmed the protein folding machinery of the ER and led to (i) distention of the ER compartment, (ii) prolonged association of misfolded proinsulin with the ER chaperone BiP and (iii) reduced secretory granule content.

In vitro, diabodies produced from the anti-HER2/neu (c-erbB-2) scFv C6.5 displayed approximately 40-fold greater affinity for HER2/neu by surface plasmon resonance biosensor measurements and significantly prolonged association with antigen on the surface of SK-OV-3 cells (t1/2 cell surface retention of > 5 h vs 5 min) compared with C6.5 scFv.

We have found that in Damon diadema (Family Phrynichidae) there is prolonged association and tolerance between mothers and their offspring, active aggregation, frequent amicable tactile interactions, and kin recognition.

Together these data suggested that the mRNAs might undergo more prolonged association with cellular components in the centre of the myofiber.

However, these earlier studies emphasized the enhanced/prolonged signaling by the mutant receptor and its prolonged association with β-Arrestin 2 in comparison with the WT receptor.

Stronger cooperation within broods might promote prolonged associations of juveniles in S. tentoriicola and may underlie the loss of pre-mating dispersal apparent in the permanent social spiders [ 34], especially when the costs of dispersal are high [ 35].

In addition, different pollutants were more strongly associated with one sex: CO with a slightly stronger and prolonged lag association only in boys during warm seasons, and NO2 and PM10 with significant associations only in girls.

Parasites are organisms that inhabit the body and benefit from a prolonged, close association with the host.

Anticyclones are responsible for periods of little or no rain, and such periods may be prolonged in association with blocking highs.

Qualitatively, the residence time of GFP-GBF1 labeled structures in the evanescent plane was also much longer in the E794K mutant (Figure 8C), which is consistent with previous reports that describe the prolonged membrane association of this cycling-defective protein [46], [47].