Sentence examples for prolonged and continuous from inspiring English sources

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To obtain maximal therapeutic effects, the prolonged and continuous administration is required.

A phase I and pharmacokinetic study was performed to determine the toxicities and maximum tolerated dose of prolonged and continuous intraperitoneal 5-FU in patients with peritoneal carcinomatosis.

Instead, factors determining successful prolonged and continuous delivery of the analog are likely to include a balanced number of inter-hexamer interactions and moderate crystal stability.

This is particularly likely in patients with knee OA given their propensity for being overweight or obese and the need for prolonged and continuous use of the insole whilst weightbearing given the chronicity of the disease.

The main advantage of using chlorhexidine is its wide antimicrobial spectrum, acting on both Gram-positive and Gram-negative microorganisms, and its prolonged and continuous effect even in the presence of blood and other body fluids [ 8].

Case-patients who agreed to clinical assessment and treatment represented a challenge for clinicians because they required prolonged therapy and continuous monitoring for antimicrobial drug resistance.

Moreover, the referral of the subgroup of patients in need for surgery was not unacceptably prolonged and the management program ensured continuous evaluation of pharmacological and surgical management, and provides the basis for scientific research.

In this model, acute infection may be clinical or subclinical followed by a prolonged and commonly lifelong period of continuous viral replication as seen in all cases of HIV infection, most cases of hepatitis C virus (HCV) infection, and less commonly in adult-acquired HBV infection.

Due to the intracellular distribution of MTX, renal replacement should be a continuous modality with high blood flow rates or possibly prolonged and repeated IHD.

The ovations were prolonged and deserved.