Sentence examples for prolongation required from inspiring English sources

Questionnaires were mailed to practicing obstetricians, asking the magnitude of pregnancy prolongation required to introduce treatments into practice.

Pearson Chi Squared tests were used to examine differences between groups (for example clinicians practicing in different settings) in the proportion of respondents giving different choices of gestational prolongation required to change practice.

The International Conference on Harmonization E14 guidance for the clinical evaluation of QT/QTc interval prolongation requires almost all new drugs to undergo a dedicated clinical study, primarily in healthy volunteers, the so-called TQT study.

For QTc prolongation, Grade 3 QTc prolongation was required in three of six pts to declare a dose-limiting toxicity, while all Grade 4 QTc prolongations were declared as dose-limiting toxicity.

The marked G1-phase prolongation obviously required a reduction in metabolic flux and anabolic pathways, including protein synthesis, which in turn might be reflected in decreased overall RNA synthesis.

In general, this classification consists in 5 grades: (1) mild if no therapy is necessary, (2) moderate if specific treatment is needed, (3) severe when hospitalization or its prolongation was required, (4) very severe if a reaction was potentially life-threatening, and (5) when contributed to the patient's death.

Of the 22 serious adverse events, 18 occurred in study A2401, in which prolongation of hospitalization required a classification of serious adverse event.

Specifically, evidence suggesting that correction of INR prolongation is not required in the prophylactic clinical situation could significantly alter current practice and potentially reduce demand for FFP.

Gathering pharmacokinetic data for the parent molecule as well as determining the contribution of metabolites to observed QT interval prolongations, would require a separate effort and was beyond the scope of this particular QT concordance exercise.

Within the proposed two-level framework, a prolongation operator, which is required to linearize the convective terms at the fine mesh level using the convergent Navier Stokes solutions computed at the coarse mesh level, is rigorously derived to increase the prediction accuracy.

Only when using Ringer's lactate for both the first and second fluid infusion was there a significant prolongation of the time required for overcoming the surgery-induced paralytic ileus and food intolerance.