Your English writing platform
Discover LudwigExact(29)
Our finding that patients' main reason to opt for chemotherapy to possibly prolong their life is noteworthy since life prolongation by chemotherapy is often modest at most.
This is probably the first report which clearly demonstrates the Tp-e interval prolongation by sevoflurane not only in healthy people but also in patients with LQTS.
Despite this increasing focus on QT prolongation by the pharmaceutical industry and drug regulatory agencies, there remains little information available to clinicians to guide them in risk assessment of a drug-induced prolonged QT [1].
Recently published results from the long-term follow-up of Radiation Therapy Oncology Group (RTOG) trial 9802 demonstrated medically meaningful and statistically significant survival prolongation by adding chemotherapy with procarbazine, lomustine (CCNU), and vincristine after radiotherapy (RT) vs RT alone for "high -risk patients (median 13.3 vs 7.8 years, high -riskio = 0.59, patients).
Study design: Open pilot study assessing the prolongation by H.E.L.P.-apheresis in 6 women (30 41 years) with very preterm PE (24+4 to 27+0 gestational weeks (GW)) (NCT01967355) compared to a historic control-group matched for GW at admission (<28 GW; n = 6).
Further analysis indicated a multifactorial action potential prolongation by quinidine: (1) decreasing fast repolarization with IC50 of 1.1·10− 6 M; (2) reducing maximum upstroke velocity with IC50 of 2.6·10− 6 M; and (3) suppressing spontaneous activity with EC50 of 3.8·10− 6 M.
Similar(31)
In another study (Braam et al. 2010), QT interval prolongation caused by several agents and drugs was measured by multi-electrode array (MEA) chips seeded with microdissected cardiac clusters consisting of mainly ventricle-like cells.
The foregoing data do not distinguish whether the observed growth inhibition is induced by ligand-dependent ErbB2 co-activation per se or, alternatively, by the downstream consequences of growth factor signal prolongation induced by ligand-dependent ErbB2 heterodimerisation.
There is a concern about cardiac rhythm disorders related to QTc interval prolongation induced by methadone.
This prolongation disappeared by day 90.
QT interval prolongation induced by drugs is known as drug-induced QT interval prolongation.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com