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In our neonatal starvation study, we observed that the Pgpep1 transcript was decreased to about half normal levels, which could potentially prolong the function of TRH and neurotensin.
Will concomitant realignment increase the chance of establishing stability or would staging the two procedures not only eliminate the risks associated with the combined procedure in a significant number of patients, but also prolong the function of these patients by putting off a realignment procedure with a time-and-demand-limited survival curve?
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Addition of testicular hyaluronidase (0.4 mg/mL) to livers preserved for 24 hours in cold UW solution followed by brief exposure to Ringer's lactate both prolonged the function of the grafted livers and improved their viability (4 of 10 grafts survived, compared with 0 of 10 in the control group).
Careful management of blood pressure in a patient with a positive predictive test significantly prolongs the functioning life of a patient's native kidneys and postpones the need for renal replacement therapy.
In addition, human MSCs activated by poly(I C) or LPS significantly prolong the survival and function of neutrophils, indicating a role of MSCs in recruiting peripheral blood neutrophils and enhancing their inflammatory activity to respond to microbial challenge.
Use of materials that can locally inhibit the interaction between the permeable small cytotoxic factors and islet cells may prolong the viability and function of encapsulated islet grafts.
Although metformin failure may occur more rapidly in clinical practice than in clinical trails, initiating it soon after diabetes diagnosis and while A1C is low might preserve β-cell function, prolong the effectiveness of metformin, reduce lifetime glycemic burden, and prevent diabetes complications.
Following prolonged and strenuous exercise, the function of the immune system is impaired for several hours [ 14, 15], but on the other hand, the regular exercise training has been shown to increase resistance to infections [ 16– 16].
It is primarily active during lytic replication and its expression pattern suggests that it may function to prolong the survival of cells in which lytic infection is present.
Overexpression of PGC-1 α could significantly improve motor function and prolong the lifespan of ALS mice, which indicate that PGC-1 α may play a protective role in ALS [ 25].
Blocking of photoreceptor apoptosis is one of the possible therapeutic approaches to protect the morphology and function of the retina and prolong the period of useful vision in patients.
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