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Conclusion: Norethindrone acetate protects the endometrium from estrogen-induced hyperplasia and changes in proliferative status.
[18F]ISO-1 may be capable of stratifying patients into groups of high or low proliferative status, which is expected to be useful in selecting patients who are likely to respond to cell cycle specific chemotherapeutics (Dehdashti et al., 2013).
Several studies have shown that σ2 receptor expression is a biomarker for the proliferative status of tumour cells and solid tumours [32, 35, 36], and are 8 to 10 times overexpressed in proliferative cells compared to quiescent cells [32, 35].
The high correlation of tumor-to-muscle ratio to Ki-67 scores indicates that [18F]ISO-1 may provide a novel method for imaging the proliferative status of solid tumors.
Given that proliferative status in the FNA material is not always assessable, we designed and performed on FNA leftover a multiprobe genomic signature for proliferation genes that strongly correlated with the Ki67 index examined on histologic material.
However, these plaques are in a highly proliferative status.
However, the suppression again seemed to be dependent on the proliferative status of WJMSCs.
We next investigated the proliferative status of the leukemia/lymphoma cells present in these animals.
The proliferative status of HSCs also affects their "transplantability" and engraftment.
These data indicate that proliferative status was not correlated with the abnormal localization of chromosome 13 in the fibroblast cultures.
This study is the first demonstration that Id2 phosphorylation status determines the proliferative status of skeletal muscle myoblasts.
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