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EGF is a proliferative factor of TSC2−/− ASM cells.
Therefore, we do not think a proglucagon product is the primary proliferative factor to α cells.
FGF2 is a potent and necessary proliferative factor in adult NPCs (Chipperfield et al., 2002).
Thus, PSAT1 functions as pro-survival and proliferative factor in tumorigenesis.
PDGF is the best characterized and the most active proliferative factor for OPCs.
PDGF is another potent proliferative factor for hepatic stellate cells and myofibroblasts during liver fibrogenesis [ 17].
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Additionally, the proliferative factors PCNA and CCNA were reduced.
Moreover, these cells have diminished capabilities in conditioning media with proliferative factors.
Indeed, we found in the present study that the proliferative factors were decreased in resistant NSCLC.
Nevertheless, there is an increase in number of cells with proliferative potential in joints with osteoarthritis due to cell communication and release of growth and proliferative factors.
ANG II increases the expression of some proliferative factors, including platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF).
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