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Mechanistically, these interventions act by blocking the proliferative effect of ER, which makes their anti-proliferative effect as potent as the combination of PI3K and ER inhibitors.
Bergapten has also been known to counteract the proliferative effect and cause apoptosis of breast cancer cells [3].
This proliferative effect was reversed by the addition of recombinant TNF-α.
HA synthesis inhibitor, 4-methylumbelliferone inhibited the proliferative effect of RAL.
We therefore reasoned that CNTF or BDNF should have a similar proliferative effect in vitro.
It is possible that the proliferative effect of PAR2 is countered via regulating other genes.
Similar(19)
Figure 1 Anti-proliferative effect of Mallotus phillipensis extracts.
Sensitivity of each cell line to the anti-proliferative effect of erlotinib was determined in vitro.
Inhibiting LDH-5 activity has an anti-proliferative effect on cancer cells.
MTT assay was performed to examine the anti-proliferative effect of juglone.
MX-68 treatment produced a similar anti-proliferative effect to that of methotrexate.
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