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Patients with a diverse pattern of response had more vigorous SFMC proliferation than PBMC proliferation to all antigens tested.
Proliferation to all of the antigens was more vigorous in the SFMCs than in the PBMCs in the group of patients who exhibited a diverse response.
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The effects of hypoxia and bFGF supplementation were found to dramatically and synergistically increase cell proliferation compared to all other treatment groups at day 7 and these differences increase over time.
The B-1 cell proliferation response to all the TLR ligands was less than that of the B-2 cell response and in all cases could be enhanced by neutralization of the inhibitory effects of IL-10.
eSc-MSC showed significantly enhanced proliferation compared to all other cultured cell populations (p-values < 0.0021).
The BSA control group (n = 16) had a significantly lower rate of proliferation compared to all of the PDGF-treated experimental groups.
Regarding adaptive immunity, the decreases in B cell/plasma cell number, function (antibody production), and proliferation could all translate to a blunted adaptive immune response to pathogen, leading to increased severity and time span of infection.
Stress, accumulation of toxic compounds, infection, autoimmunity, mutations, altered cellular environment and impaired melanocyte migration and/or proliferation may all contribute to vitiligo etiopathogenesis in varying proportions.
In ALL, miR-125b has an important role in early hematopoietic development (Shaham et al, 2012); miR-124a contributes to the abnormal proliferation of ALL cells (Agirre et al, 2009), and knockdown of miR-17-92 miR-17-92 miR-17-92hown to inclusterslucocorticoid-mediated apoptosis in ALL cell lines (Molitoris et al, 2011).
T cells that had been previously exposed to CTLA4-KDEL or IDO-expressing CBK DCs showed minimal proliferation at all time points to CBK DCs (Fig. 3A).
Proliferation is common to all three phenotypes occurring in the chick epiblast.
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