Sentence examples for proliferation sensitivity from inspiring English sources

Contrary to the safety aspects, for which solutions were uncovered in the European MOST project, it was felt necessary for the safeguards aspects to complete a proliferation sensitivity study and to analyse innovative solutions for proliferation-resistance.

Germ cells of smc-5 -defective animals show reduced proliferation, sensitivity to perturbed replication, chromatin bridge formation, and accumulation of RAD-51 foci that indicate the activation of homologous recombination at DNA double-strand breaks.

PPARs are members of the nuclear receptor superfamily, actively involved in immunoregulation through their ability to regulate membrane lipid composition, cell proliferation, sensitivity to apoptosis, energy homeostasis, and various inflammatory transcription factors, mainly through their transrepression capabilities [ 23].

The present study was designed to investigate the role of GGT and of intracellular GSH levels in modulating proliferation and sensitivity to cisplatin of melanoma cells.

High intensity expression of PD-1 on CD8+ T cells has correlated most consistently with poor proliferation and sensitivity to apoptosis [34].

RAPA favors Treg expansion and survival by differentially regulating signaling, proliferation and sensitivity to apoptosis of human effector T cells and Treg after TCR/IL-2 activation.

Because Jak-3 is critical to IL2-dependent signaling and proliferation, its sensitivity to PGE2 may make it a prime target for suppressing IL2-dependent cell cycle progression in T cells.

Primary cultures of OSE cells from these mice were also established to determine the impact of combined inactivation of these genes on their rate of proliferation and sensitivity to cisplatin.

Compared to patient tumors, cell lines often exhibit increased proliferation, altered sensitivity to chemotherapy and reduced cellular heterogeneity [ 14- 16].

However, this is clearly not the only variable, as some cells appeared to increase their proliferation and sensitivity under low oxygen pressure.

Thus, control of endogenous ROS level and the regulation of MAPK pathway may involve in proliferation and sensitivity to stress stimuli including anticancer drugs in cancer cells.