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Furthermore, the proliferation promotion effect of HRC was significantly abolished by the MEK inhibitor U0126.
And the chemical inhibition of DNA methylation significantly restrained such proliferation promotion.
These findings indicated that DNA methylation knockdown blocked the proliferation promotion by the Hiwi overexpression in CRC cells.
Constitutive STAT3 activation has been linked to cancer initiation, proliferation, promotion of angiogenesis and inhibition of apoptosis.
Endothelin-1 causes vasoconstriction and vascular smooth muscle cell proliferation, promotion of inflammation and fibrosis [ 5, 6].
Activation of the EGFR is involved in malignant transformation and tumour growth through the inhibition of apoptosis, cellular proliferation, promotion of angiogenesis, and metastasis.
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NSC obtained from the rat embryonic striatum was cultured directly on the array to screen for cell adhesion, proliferation, and promotion of neuronal and glial specification.
Corneal nerves bear substantial relevance to clinicians and scientists alike, given their pivotal roles in regulation of corneal sensation, maintenance of epithelial integrity, as well as proliferation and promotion of wound healing.
Despite the proliferation and promotion of crystals, science scoffs at the idea that these rocks hold magical powers.
Collectively, C/EBPβ was shown to be essential for cessation of proliferation and promotion of hypertrophic differentiation, suggesting arrest of the cell cycle and exit from it.
Other factors (including cell proliferation and promotion by exogenous agents) may play important additional roles.
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