Sentence examples for proliferation limit from inspiring English sources

This proliferation limit is important as a tumor suppressive mechanism, but also contributes to the degenerative conditions associated with cellular aging.

The future will show whether non-invasive mechanisms will be identified to break the proliferation limit of other human differentiated non-neoplastic cell types, or whether it will emerge that B cells have singular proliferation properties that are rooted in their unique biological function.

However, their low rate of proliferation limits obtainable space-time yields due to inefficient biomass accumulation.

At the same time, CY has a strong negative effect on T cell proliferation, limiting the potential expansion of anti-tumor CD8 T cells, raising the question how a CD8 T cell-dependent anti-tumor response functions without T cell expansion.

Since it happens at a different rate and occupies space, we incorporate C d into the proliferation limiting terms in Eqs.

The most prominent finding is that the diabetic milieu leads to hyper proliferation of vSMCs such that in people with diabetes proliferation limits the efficacy of vascular interventions due to hyperplasia of vSMCs [ 2].

Normal cells undergo a limited number of successive cell growth-and-division cycles, since their proliferation is subjected to two distinct barriers: senescence, a viable state characterized by an irreversible arrest in proliferation limiting the lifespan of mammalian cells, and crisis, which involves cell death.

We argue that inactivating mutations in these genes (labeled RPPMs: repressors of proliferation/promoters of motility) results in predominantly benign growths because, while such mutations promote unconstrained proliferation, they limit the ability of neoplastic cells to migrate and invade.

The TNP-470 inhibition of microvascular proliferation may limit the development of collaterals that communicate with new feeding arteries.

Ex vivo gene therapy has the potential to reduce unnecessary cell proliferation and limit neointima formation in vascular pathologies.

Bantam promotes cell growth and proliferation by limiting expression of negative growth regulators, as well as limiting apoptosis by repressing Hid expression (Brennecke et al., 2003; Herranz et al., 2012a, b).