Activation of this pathway ('HER2+') results in increased proliferation, increased anti-apoptotic protein expression and angiogenesis, and is associated with worse prognosis (Slamon et al, 1987).
These elevated expressions of ERs are associated with dysregulation of proliferation (increased numbers of proliferating cells) [ 6].
The expression of proliferating cell nuclear antigen (PCNA), a marker for cell proliferation, increased in N12 and N20 cells.
Denis et al. reported similar results, in which proliferation increased with increasing surface hydrophilicity [14].
This study found that cell proliferation increased with the greater amount of MWCNTs.
While ECFCs adhesion and proliferation increased with substrate stiffness, no change in phenotype was observed.
Cell proliferation increased significantly by 120% at SaOS2 and 127% at EAhy926.
When treated with GKA50, a GK agonist, INS-1 β-cell prolincreased increated at basal levels of glucose.
PEG-Cys-NO hydrogels inhibited smooth muscle cell proliferation, increased endothelial cell proliferation, and inhibited platelet adhesion in vitro.
Using functional experiments, we observed decreased cell proliferation, increased apoptosis, and motility inhibition in alncRNA-infected bladder cancer cells.
In the presence of TN-C, however, acini failed to generate a normal BM, and net epithelial cell proliferation increased.
