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These transcriptional changes correlated well with functional data on cell proliferation, expression of adhesion molecules, and utilization of metabolic pathways, ultimately leading to different phenotypes.
The rate of cell proliferation was significantly increased due to presence of R-peptide, and the MSCs marker analyses using flow cytometry and immunocytochemistry staining proved the ability of R-peptide to maintain mesenchymal stem cell properties (high proliferation, expression of multipotent markers and differentiation capacity) even after long-term passage culturing.
Concomitant with enhanced GNP proliferation, expression of the Shh-target Gli1was increased greater than 10-fold (Fig. 7C).
To determine whether Akt1 expression in F3.Akt1 cells induces their own proliferation, expression of cell proliferation marker Ki-67 was examined in ICH brain sections (Figure S1).
The growth of neurites can also be achieved by inducing cAMP elevation and it is accompanied by other features in common with a neuronal phenotype, such as cessation of proliferation, expression of neuronal markers and secretion of neurotransmitters [3], [6].
The first intentionally created phESCs were derived from a blastocyst inner cell mass obtained from an unfertilized oocyte activated by chemical stimuli [3]; these cells demonstrated typical characteristics displayed by hESC, including proliferation, expression of typical markers of pluripotency and differentiation in vitro and in vivo into cells of all germ layer lineages.
Similar(46)
We had three time points with n = 3/group for cell proliferation, collagen expression, and osteopontin expression.
The infiltrating cells exhibited marked proliferation (CD71 expression) and activation (particularly LFA-1 but also CD25 expression).
Cell proliferation marker expression in the Ctnnb1 Δex3 mice correlated strongly with dysplasia and β-catenin expression.
By signaling through either HVEM or LTβR expressed on these cells, LIGHT can contribute to their proliferation and expression of chemokines, growth factors, and metalloproteinases.
The proliferation and expression of growth factors of HGF keratinocytes are abnormal.
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