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Incubation of the two different RA FLSs with SFs containing anti-GM-CSF mAb significantly impaired the SF-mediated proliferation efficacy of FLSs.
Both MCF-7 and MDA-MB-231 express the thyroid hormone receptor, the chemosensitization role of T3 in these two cell lines is thought to be mediated by the proliferation efficacy of T3.
Dinda et al. [ 38] found thyroid hormone not only enhances the phosphorylation of pRb, but also induces the c-Myc expression and mutant P53 expression, this can also explain the cell proliferation efficacy of thyroid hormone.
A comprehensive laboratory investigation of the proliferation efficacy of MSCs cultured on 4 major types of culture flasks has indicated that the most improved expansion of cultured MSCs was acquired in the flasks from Falcon, followed by those from Corning, Nunc, and Greiner, although the quality and functions of produced MSCs did not differ among the different types of flasks examined [ 16].
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With this background, we planned to synthesize a series of meta-xylyl linked bis-benzimidazolium salts to assess their anti-proliferation efficacy on human colon cancer cell line (HCT 116).
This indicates that further translational research needs to interpret anti-proliferation efficacy among the different molecular subtypes.
We propose that anti-proliferation efficacy of anti-cancer agents needs to be evaluated among different subtypes in preoperative translational trials.
Moreover, SCM/DOX showed more effective proliferation inhibition efficacy on RenCa cells than those of the DOX-loaded micelles with single component (p < 0.001).
As shown in Figure 7B, compared to free DOX · HCl, the laden micelles appeared a stronger proliferation inhibitory efficacy at equivalent DOX concentration after incubation for 48 h (p < 0.001).
The results revealed that a disulfide-rich peptide aptamer inhibited IL-6-dependent cell proliferation with similar efficacy to an anti-IL-6R monoclonal antibody.
Absolute germ cell numbers in gonad arms interpreted as proliferating were not determined, and there may be a difference in efficacy of proliferation rescue, depending on which cells carried the array.
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