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IRS-2 down-regulation can decrease the proliferation effect of YH-GKA.
The results suggest that CUR/PVP mats exhibit efficient cell proliferation effect on B16, compared to free CUR.
Therefore, the similarity of two species of Ganoderma in fatty acids may be related to their antitumoral proliferation effect.
The similarity of two species of Ganoderma in fatty acids may be related to their antitumoral proliferation effect.
The bioactivity of the G-CSF recovered was determined by the proliferation effect induced on an NSF-60 cell line.
Howerver, the content of triterpenoids and polysaccharides, main actives compounds, are significant different, though the extracts of both G. lucidum and G. sinense have antitumoral proliferation effect.
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Upregulation of miR-34b also induced apoptosis and increased the sensitivity of the cells to the anticancer drugs, whereas transfection with miR-34b-AMO, an inhibitor of miR-34b, reversed the anti-proliferation effect of sirolimus.
Histological assay also indicated that FA-TPGS2K/HDP mixed micelles showed strongly apoptosis inducing effect, anti-proliferation effect and anti-angiogenesis effect.
Histological and immunochemical analysis further demonstrated that BUF-NP-RGD exhibited improved cell apoptosis, angiogenesis inhibition, and an anti-proliferation effect.
When compared with the control and pure HCD, the MSN-HCD revealed a potential anti-proliferation effect via the synergistic effect of the drug and the MSN vehicle.
Figure 11 Anti-proliferation effect of test compounds on HCT 116 was assessed by MTT-assay.
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