Exact(2)
We also suggest a simple way to evaluate whether cell motility or proliferation drive the process, based on a non-dimensional parameter.
Subsequently, the detection of a fragile site distal to the egfr gene, sustaining uncapped telomere-less chromosomal ends, the ladder-like structure of the intrachromosomal egfr amplification and a broader range of egfr copy numbers support the assumption that dynamic chromosomal rearrangements, like breakage-fusion-bridge-cycles other than proliferation drive the gain of egfr copies.
Similar(6)
In turn, I-8 inhibited cell proliferation driven by RET wildtype and gatekeeper mutation.
Mutations in Hippo pathway components in Drosophila consistently result in an increase in cell proliferation driven by excess Yorkie in the nucleus (reviewed by Pan [44]).
The uncontrolled proliferation driven by latency III is also seen transiently in vivo.
This is likely due to inhibition of both angiogenesis and cell proliferation driven by the presence of a VEGF/VEGFR-2 autocrine loop in tumor cells.
Endometrial cancer growth at the invasive front is regulated by a higher rate of cellular proliferation, driven by the alteration in cell cycle regulation [40], [41].
Increased RANKL protein expression was positively associated with increased ductal and alveolar proliferation driven by EPT.
Related(2)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com